Glycolipids in model membranes. Spin label and freeze-etch studies

1. Several types of glycolipid are examined in lipid bilayer model membranes as part of a program to clarify their fuction in living cells. 2. Data obtained with three spin labelled derivatives of galactosyl ceramide is reported showing a fatty acid fluidity gradient similar to that obtained with phospholipid spin labels. Some possible structural implications of the observed differences are considered. 3. Results obtained using Freeze-Etch electron microscopy and hemagglutination inhibition are given showing beef brain gangliosides in lipid vesicles to be effective receptors for influenza virus.