Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bone Marrow Sampling and Transplants

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

Stem Cell Therapy for Tissue Regeneration

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

Kidney Transplant I: Introduction

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

Embryonic Stem Cells

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...

Regulation of Hematopoietic Stem Cells

Regulation of Hematopoietic Stem Cells

All blood and immune cells are produced from the multipotent hematopoietic stem cells (HSCs) by the process of hematopoiesis. However, they all have a limited life span. In addition, many are depleted in immune surveillance or combatting an injury or infection. This makes blood one of the most regenerative tissues. Hematopoiesis helps replenish these blood and immune cells, restoring the body's normal functioning. However, overproduction of blood and immune cells can make them cancerous or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

THE INCIDENCE OF URINARY TRACT INFECTION AMONG PATIENTS TREATED WITH VARIABLE DOSES OF DAPAGLIFLOZIN: A COMPARATIVE STUDY.

Georgian medical news·2025

Same author

Ultrasound-guided femoral venous access decreases vascular complications in catheter ablation procedures.

Scientific reports·2025

Same author

Quantifying upper lip height difference between two young male and female populations by direct surface measurement: Implications for gender-affirming upper lip shortening surgery.

JPRAS open·2024

Same author

Lip feminization: A review.

JPRAS open·2024

Same author

Assistance by adaptative damping on a complex bimanual task in laparoscopic surgery.

International journal of computer assisted radiology and surgery·2024

Same author

Neutrophil-to-lymphocyte ratio (NLR) variations in relationship with childhood maltreatment in patients with anorexia nervosa: a retrospective cohort study.

Eating and weight disorders : EWD·2022

Search research articles

Related Experiment Video

Updated: Jul 2, 2026

Isolation and Transplantation of Hematopoietic Stem Cells (HSCs)

Isolation and Transplantation of Hematopoietic Stem Cells (HSCs)

Published on: February 25, 2007

Hematopoietic stem cell transplantation in Egypt.

Hk Mahmoud¹, Am El-Haddad, Oa Fahmy

¹The BMT Unit, Medical Oncology Department, National Cancer Institute, Cairo University, Egypt. hossam_kamel@tedata.net.eg

Bone Marrow Transplantation

|September 25, 2008

Summary

Hematopoietic stem cell transplantation (HSCT) is a vital treatment for blood disorders. This article examines challenges and strategies for establishing successful HSCT programs in developing countries, using Egypt as a case study.

More Related Videos

Intrafemoral Injection of Human Hematopoietic Stem and Progenitor Cells into Immunocompromised Mice

Intrafemoral Injection of Human Hematopoietic Stem and Progenitor Cells into Immunocompromised Mice

Published on: December 8, 2023

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Published on: September 6, 2017

Related Experiment Videos

Last Updated: Jul 2, 2026

Isolation and Transplantation of Hematopoietic Stem Cells (HSCs)

Isolation and Transplantation of Hematopoietic Stem Cells (HSCs)

Published on: February 25, 2007

Intrafemoral Injection of Human Hematopoietic Stem and Progenitor Cells into Immunocompromised Mice

Intrafemoral Injection of Human Hematopoietic Stem and Progenitor Cells into Immunocompromised Mice

Published on: December 8, 2023

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Published on: September 6, 2017

Area of Science:

Hematology
Transplantation Medicine
Global Health

Background:

Hematopoietic stem cell transplantation (HSCT) is a recognized treatment for hematological disorders.
Resource limitations pose significant challenges for HSCT in developing countries.
The Egyptian HSCT program, initiated in 1989, has expanded significantly since 1997.

Purpose of the Study:

To highlight critical considerations for hematopoietic stem cell transplantation (HSCT) in developing nations.
To share experiences from Egypt's HSCT program as a potential model for other developing countries.
To address the gap between available resources and treatment possibilities in global HSCT practices.

Main Methods:

Review of 18 years of experience and over 1300 HSCT procedures.
Analysis of the Egyptian HSCT program's development and current status.
Focus on practical issues relevant to resource-limited settings.

Main Results:

Egypt has performed 1362 HSCTs by June 2007, with 80% allogeneic and 20% autologous.
Significant growth in transplant rates occurred after the establishment of the Nasser Institute's HSCT unit in 1997.
Seven other centers in Egypt primarily conduct autologous transplants.

Conclusions:

Successful HSCT programs can be developed in resource-limited settings with strategic planning and experience.
The Egyptian experience offers valuable insights for establishing and expanding HSCT services globally.
Addressing resource disparities is crucial for advancing HSCT accessibility in developing countries.