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Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
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Models of Health Promotion and Illness Prevention II01:18

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Related Experiment Video

Updated: Jul 2, 2026

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
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Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

The View-Master Health Study Focus Groups.

Kathleen Krall1, Jae Douglas, Nancy A Perrin

  • 1Willamette Family Medical Center, Portland, OR 97219, USA. Krallfamily@comcast.net

Journal of Environmental Health
|August 30, 2008
PubMed
Summary
This summary is machine-generated.

Former workers exposed to trichloroethylene (TCE) recalled minimal safety training and favored using co-workers for exposure data. This information aids in developing better exposure assessment tools for occupational health.

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Using Visual and Narrative Methods to Achieve Fair Process in Clinical Care
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14:32

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Published on: February 16, 2011

Area of Science:

  • Environmental Health
  • Occupational Health
  • Toxicology

Background:

  • Trichloroethylene (TCE) is a common groundwater contaminant with strengthened evidence of carcinogenic risk and health hazards.
  • High levels of TCE were detected at an Oregon work site in 1998, necessitating further investigation into worker exposure.
  • Concerns regarding occupational exposure to TCE highlight the need for improved exposure assessment methods.

Purpose of the Study:

  • To gather qualitative data from former workers regarding their experiences with TCE exposure.
  • To understand workers' perceptions of safety procedures, medical record access, and proxy accuracy.
  • To inform the development of an exposure assessment interview tool for TCE-contaminated work sites.

Main Methods:

  • Qualitative content analysis of focus group discussions with 13 former workers from an Oregon site.
  • Exploration of plant processes, safety protocols, and worker attitudes towards health information.
  • Assessment of preferred sources for proxy exposure information and opinions on medical record accessibility.

Main Results:

  • Workers reported limited recall of safety policies, training, or support for safety controls.
  • Co-workers and family members were identified as preferred sources for proxy exposure information.
  • Workers generally supported granting access to their medical records.
  • Job mobility underscored the need for job or task-based exposure matrices.

Conclusions:

  • Former workers' experiences highlight gaps in occupational safety communication and training related to TCE exposure.
  • Worker input is valuable for developing effective exposure assessment tools, emphasizing the utility of proxy information and medical record access.
  • Findings will guide the creation of a more accurate and worker-centered exposure assessment interview tool for similar occupational settings.