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Updated: Jul 2, 2026

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
Published on: March 17, 2014
Relationship of pneumocystis antibody response to severity of chronic obstructive pulmonary disease
Alison Morris1, Mahesh Netravali, Heather M Kling
1Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA. morrisa@upmc.edu
Abstract:
Pneumocystis colonization has been associated with severity of chronic obstructive pulmonary disease (COPD). The relationship of Pneumocystis antibody status to COPD severity has not been investigated, but antibody levels might relate to both colonization susceptibility and COPD progression. We investigated anti-Pneumocystis antibody titers and airway obstruction in a cohort of patients with COPD. Undetectable anti-Pneumocystis antibody titer was an independent predictor of more-severe airway obstruction, although use of inhaled corticosteroids is a possible confounder of this effect.
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