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Protruding atheromas in the thoracic aorta and systemic embolization.
P A Tunick1, J L Perez, I Kronzon
1New York University Medical Center, New York.
Annals of Internal Medicine
|September 15, 1991
Summary
Protruding atheromas in the thoracic aorta are a significant risk factor for embolic events like stroke. Transesophageal echocardiography can identify these atheromas, aiding in diagnosis and prevention strategies.
Area of Science:
- Cardiovascular Medicine
- Neurology
- Diagnostic Imaging
Background:
- Systemic embolization is a major cause of stroke and other embolic events.
- Identifying modifiable risk factors for embolic events is crucial for preventative strategies.
Purpose of the Study:
- To investigate whether protruding atheromas in the thoracic aorta are an independent risk factor for systemic embolization.
Main Methods:
- A case-control study was conducted with 122 patients experiencing embolic symptoms and 122 matched controls.
- Transesophageal echocardiography was used to detect protruding atheromas in the thoracic aorta.
Main Results:
- Protruding atheromas were strongly associated with embolic symptoms (OR, 3.2; P < 0.001).
- Atheromas with mobile components were only found in patients with embolic symptoms.
- Protruding atheromas remained an independent risk factor after accounting for hypertension and diabetes.
Conclusions:
- Protruding atheromas in the thoracic aorta are a detectable cause of strokes, transient ischemic attacks, and peripheral emboli.
- Transesophageal echocardiography is a valuable tool for identifying this risk factor.
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