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Updated: Jul 2, 2026

Evaluation of the Efficacy And Toxicity of RNAs Targeting HIV-1 Production for Use in Gene or Drug Therapy
Published on: September 5, 2016
Silencing HIV-1 In Vivo
1Institute of Virology, University of Ulm, 89081 Ulm, Germany. frank.kirchhoff@uniklinik-ulm.de
Abstract:
RNA interference holds great promise for antiviral therapy, but delivering effective quantities of small interfering RNAs (siRNAs) into the right target cells in vivo represents a major challenge. Kumar et al. (2008) now report a technique to target siRNAs specifically to T cells to suppress viral infection in a humanized mouse model of HIV/AIDS.
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