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Related Experiment Videos

Basaloid monomorphic adenomas.

J G Batsakis1, M A Luna, A K el-Naggar

  • 1Dept of Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030.

The Annals of Otology, Rhinology, and Laryngology
|August 1, 1991
PubMed
Summary
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Basaloid monomorphic adenomas, particularly dermal analogue types, predominantly affect major salivary glands like the parotid. These tumors frequently recur and may exhibit malignant transformation.

Area of Science:

  • Oncology
  • Pathology
  • Salivary Gland Neoplasms

Background:

  • Monomorphic adenomas are classified into basaloid and nonbasaloid subtypes.
  • Basaloid monomorphic adenomas primarily occur in major salivary glands, especially the parotid gland.
  • Dermal analogue monomorphic adenomas represent a distinct subgroup of basaloid adenomas, histologically resembling skin eccrine tumors.

Purpose of the Study:

  • To characterize the key features and clinical behavior of dermal analogue monomorphic adenomas.
  • To highlight their unique subset within basaloid adenomas.
  • To discuss their potential for multifocality, recurrence, and malignant change.

Main Methods:

  • Histopathological analysis of monomorphic adenoma subtypes.
  • Review of clinical data pertaining to tumor behavior, including recurrence and malignant transformation.

Related Experiment Videos

  • Comparison of dermal analogue adenomas with other basaloid monomorphic adenomas and eccrine tumors.

    • Main Results:

    • Basaloid monomorphic adenomas, excluding canalicular adenoma, are predominantly tumors of major salivary glands.
    • Dermal analogue monomorphic adenomas exhibit characteristic histologic similarities to eccrine skin tumors.
    • These specific adenomas are frequently multifocal, prone to recurrence, and possess the potential for malignant transformation.

    Conclusions:

    • Dermal analogue monomorphic adenomas are a unique and clinically significant subset of basaloid salivary gland tumors.
    • Their tendency for recurrence and malignant change warrants careful monitoring and management.
    • These tumors can be associated with a broader salivary-cutaneous tumor diathesis.