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Updated: Jul 2, 2026
08:01
A Method for Manipulating Blood Glucose and Measuring Resulting Changes in Cognitive Accessibility of Target Stimuli
Published on: August 12, 2016
Glycemic instability and spontaneous energy intake: association with knowledge-based work
Jean-Philippe Chaput1, Vicky Drapeau, Paul Poirier
1Division of Kinesiology (PEPS), Department of Social and Preventive Medicine, Laval University, Quebec City, Quebec, Canada, G1K 7P4.
Psychosomatic Medicine
|August 30, 2008
Summary
Knowledge-based work (KBW) significantly increases energy intake and fluctuates glucose and insulin levels. This cognitive demand may contribute to long-term weight gain and metabolic health issues.
Area of Science:
- Human physiology
- Metabolic health
- Cognitive science
Background:
- Knowledge-based work (KBW) is prevalent, yet its physiological effects on energy balance and glucose homeostasis remain under-documented.
- Understanding these impacts is crucial for public health and occupational wellness.
Purpose of the Study:
- To investigate the acute effects of KBW on spontaneous energy intake.
- To assess the impact of KBW on glucose homeostasis, including plasma glucose, insulin, and cortisol levels.
Main Methods:
- A within-subjects experimental design was employed with 14 female students.
- Participants underwent three 45-minute conditions: rest, reading/writing, and computerized testing, followed by an ad libitum buffet.
- Plasma glucose, insulin, cortisol, and appetite markers were measured across conditions.
Main Results:
- Energy intake increased significantly (p < .05) after reading/writing and computerized testing compared to rest.
- Cortisol levels were significantly higher (p < .05) during KBW conditions.
- Plasma glucose and insulin levels showed significantly greater variations (p < .01) compared to the control condition.
Conclusions:
- KBW acutely increases spontaneous energy intake and promotes greater fluctuations in plasma glucose and insulin.
- These findings identify KBW as a potential risk factor for positive energy balance and long-term weight gain.
- Further research into metabolic and hormonal responses to cognitive load is warranted.
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