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Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
Published on: March 3, 2023
Dominance of blaCTX-M within an Australian extended-spectrum beta-lactamase gene pool
Zhiyong Zong1, Sally R Partridge, Lee Thomas
1Centre for Infectious Diseases and Microbiology, University of Sydney, Sydney, New South Wales, Australia.
Abstract:
bla(CTX-M) genes, particularly bla(CTX-M-15), are the dominant extended-spectrum beta-lactamase (ESBL) genes among clinical isolates of Escherichia coli and Klebsiella pneumoniae in Sydney, Australia, where we also found one example of bla(CTX-M-62), encoding a novel enzyme conferring ceftazidime resistance. ESBL genes were present in diverse community isolates and in a variety of associated conjugative plasmids.
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