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Related Concept Videos

Spinal Cord Injury ll: Pathophysiology01:14

Spinal Cord Injury ll: Pathophysiology

Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
Secondary Spinal Cord Injury llI: Pathophysiology01:25

Secondary Spinal Cord Injury llI: Pathophysiology

Early Ischemia and Ionic ImbalanceWithin minutes of spinal cord injury, a secondary cascade begins, progressing over hours to weeks. Vascular damage reduces blood flow, causing ischemia and mitochondrial dysfunction. ATP depletion leads to ion pump failure, membrane depolarization, sodium influx, potassium efflux, and water accumulation, resulting in cellular swelling. Increased intracellular calcium further disrupts mitochondria and accelerates cellular injury.Excitotoxicity and Neuronal...

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Related Experiment Video

Updated: Jul 2, 2026

Establishing a Mouse Contusion Spinal Cord Injury Model Based on a Minimally Invasive Technique
07:17

Establishing a Mouse Contusion Spinal Cord Injury Model Based on a Minimally Invasive Technique

Published on: September 7, 2022

International bowel function basic spinal cord injury data set.

K Krogh1, I Perkash, S A Stiens

  • 1Neurogastroenterology Unit, Department of Hepatology and Gastroenterology V, Aarhus University Hospital, Aarhus, Denmark. krogh@as.aaa.dk

Spinal Cord
|August 30, 2008
PubMed
Summary
This summary is machine-generated.

An International Bowel Function Basic Spinal Cord Injury (SCI) Data Set was developed by experts to standardize bowel function data collection. This essential tool aims to improve care and research for individuals with SCI.

Related Experiment Videos

Last Updated: Jul 2, 2026

Establishing a Mouse Contusion Spinal Cord Injury Model Based on a Minimally Invasive Technique
07:17

Establishing a Mouse Contusion Spinal Cord Injury Model Based on a Minimally Invasive Technique

Published on: September 7, 2022

Area of Science:

  • Neuroscience
  • Gastroenterology
  • Rehabilitation Medicine

Background:

  • Bowel dysfunction is a common and significant complication following spinal cord injury (SCI).
  • Standardized data collection is crucial for advancing research and clinical practice in SCI bowel management.
  • Existing methods for assessing bowel function in SCI lack uniformity, hindering comparative studies and consistent care.

Purpose of the Study:

  • To establish a consensus-based, minimal data set for bowel function in individuals with SCI.
  • To create a standardized format for collecting and reporting bowel function information in both clinical practice and research settings.
  • To facilitate consistent and comparable data acquisition for improved SCI patient outcomes.

Main Methods:

  • An international expert working group, comprising members from the American Spinal Injury Association (ASIA) and the International Spinal Cord Society (ISCoS), was convened.
  • A draft data set was developed and underwent rigorous review by multiple committees, including the International SCI Standards and Data Sets Executive Committee, ISCoS Scientific Committee, and the ASIA Board.
  • The draft data set was further disseminated for international review via professional organizations and public websites, allowing for extensive feedback and refinement.

Main Results:

  • The developed International Bowel Function Basic SCI Data Set comprises 12 essential items.
  • Key data points include: date of collection, presence of gastrointestinal/anal sphincter dysfunction, history of GI surgical procedures, awareness of defecation urge, defecation methods, bowel care routines, defecation frequency, fecal incontinence frequency, need for continence aids, relevant medications, laxative use, and perianal issues.

Conclusions:

  • The International Bowel Function Basic SCI Data Set provides a standardized framework for assessing bowel function in SCI.
  • This data set is expected to enhance the quality and comparability of research data and improve clinical management of bowel issues in SCI patients.
  • Adoption of this data set will promote consistency in data collection, ultimately benefiting the SCI community through better evidence-based care.