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Published on: May 2, 2018
Sequencing and bacterial expression of a novel murine alpha interferon gene
1Shanghai Institute of Biochemistry, Chinese Academy of Sciences, 200031, Shanghai, China.
Science in China. Series C, Life Sciences
|June 1, 1997
Abstract:
A murine new alpha interferon gene (mIFN-alphaB) was found by primer-based sequencing method in a murine genomic DNA library. The gene was cloned and its sequence was determined. It was expressed inEscherichia coli under the control of the P(L) promoter which resulted in antiviral activity on mouse L-cells. The sequence of mIFN-alphaB has been accepted by GENEBANK.

