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Published on: August 26, 2025
Multiple mycotic aneurysms of the pulmonary arteries resolving with conservative management: multislice CT
Thuc-Nhi Wilson1, Khimseng Tew, Ajay Taranath
1Department of Radiology, The Queen Elizabeth Hospital, South Australia, Australia.
Abstract:
Mycotic pulmonary artery aneurysms are rare but potentially fatal complications of infective endocarditis. Three mycotic aneurysms developed in a 22-year-old female patient who had a history of intravenous drug use. She suffered from Staphylococcus aureus pneumonia and infective endocarditis. The patient was managed conservatively with antibiotics. She did not have hemoptysis during a prolonged hospital stay. Several multislice computed tomography examinations were performed to follow these aneurysms over a period of 19 months. The 2 smaller aneurysms had resolved by 9 weeks postdevelopment. The largest aneurysm was stable at 9 weeks and was smaller at 19 months, but it had not yet completely resolved. The literature on this rare condition was reviewed and its prognosis and management were discussed.
Insights
This case study shows conservative antibiotic management for three mycotic pulmonary artery aneurysms in a patient with infective endocarditis, with most resolving over 19 months.
Area of Science:
- Cardiology
- Infectious Diseases
- Radiology
Background:
- Mycotic pulmonary artery aneurysms are rare, life-threatening complications of infective endocarditis.
- Intravenous drug use is a significant risk factor, often associated with Staphylococcus aureus infections.
Observation:
- A 22-year-old female with a history of intravenous drug use developed Staphylococcus aureus pneumonia and infective endocarditis.
- Three mycotic aneurysms in the pulmonary artery were identified and monitored over 19 months using multislice computed tomography.
- The patient was treated conservatively with antibiotics and remained free of hemoptysis.
Findings:
- Two smaller aneurysms resolved within 9 weeks.
- The largest aneurysm showed partial resolution at 19 months but did not completely resolve.
- Conservative management with antibiotics demonstrated potential efficacy in aneurysm resolution.
Implications:
- This case highlights the possibility of successful conservative management for mycotic pulmonary artery aneurysms.
- Long-term imaging follow-up is crucial for monitoring aneurysm progression and resolution.
- Understanding the natural history and management options for this rare condition is vital for clinical practice.
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