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Updated: Jul 2, 2026
05:59
Green Synthesis of Quinoline-Based Ionic Liquid
Published on: September 27, 2024
Long-alkyl-chain quaternary ammonium lactate based ionic liquids
Jacek Cybulski1, Anna Wiśniewska, Anna Kulig-Adamiak
1Industrial Chemistry Research Institute ul. Rydygiera 8, 01-793 Warsaw, Poland.
Chemistry (Weinheim an Der Bergstrasse, Germany)
|August 30, 2008
Summary
New quaternary ammonium lactate ionic liquids show potent antibacterial and antifungal activity, comparable to benzalkonium chloride. Didecyldimethylammonium (DDA) and benzalkonium (BA) lactates are effective against bacteria and fungi but not for wood preservation.
Area of Science:
- Materials Science
- Organic Chemistry
- Biochemistry
Background:
- Ionic liquids (ILs) are salts with low melting points, offering unique properties.
- Quaternary ammonium compounds (QACs) are known for their antimicrobial and surfactant properties.
Purpose of the Study:
- To synthesize and characterize novel quaternary ammonium lactate-based ionic liquids.
- To evaluate their efficacy as antimicrobial agents, insect-feeding deterrents, and wood preservatives.
- To assess their toxicity.
Main Methods:
- Synthesis of Didecyldimethylammonium (DDA) and Benzalkonium (BA) D,L- and L-lactates.
- Characterization of the synthesized ionic liquids.
- Antimicrobial susceptibility testing against Streptococcus mutans and Candida albicans.
- Insect feeding deterrence assays.
- Wood preservation efficacy tests.
- Toxicity studies.
Main Results:
- DDA and BA lactates are air-stable, hydrophilic, and surface-active.
- DDA lactates demonstrated significant antibacterial and antifungal activity, particularly against Streptococcus mutans and Candida albicans.
- Activities were comparable or superior to benzalkonium chloride.
- The compounds showed effectiveness as insect-feeding deterrents.
- Poor performance was observed in wood preservation applications.
- Toxicity profiles were evaluated.
Conclusions:
- Quaternary ammonium lactate ionic liquids, especially DDA lactates, represent a promising new class of antimicrobial agents.
- Their efficacy extends to insect deterrence, but they are unsuitable for wood preservation.
- Further toxicological evaluation is warranted.
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