Carotid angioplasty and stenting in octogenarians: is it safe?
M Henry1,2, I Henry3, A Polydorou4
1Cabinet de Cardiologie, Nancy, France.
Insights
Carotid artery stenting (CAS) in octogenarians shows comparable safety to younger patients. Meticulous technique and protection devices are crucial for successful CAS in the elderly.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Geriatric Medicine
Background:
- Elderly patients face increased risks with carotid endarterectomy.
- Carotid artery stenting (CAS) is an alternative revascularization procedure.
Purpose of the Study:
- To evaluate the safety and efficacy of CAS in octogenarians.
- To compare CAS-related risks in patients aged 80 and above versus younger patients.
Main Methods:
- A retrospective analysis of 930 CAS procedures in 870 patients.
- Patients were stratified into two groups: <80 years (749 patients) and >80 years (121 patients).
- Outcomes assessed included 30-day neurological complications, death, and myocardial infarction (MI), with and without protection devices.
Main Results:
- Technical success rates were high in both groups: 804/806 (<80 years) and 123/124 (>80 years).
- The composite endpoint of death/stroke/MI was 1.8% in patients <80 years and 17% in patients >80 years without protection.
- In patients >80 years, the death/stroke/MI rate was 17% without protection and not specified with protection, but no major stroke or death occurred.
Conclusions:
- CAS can be safely performed in octogenarian patients.
- Careful patient selection, meticulous technique, and the use of protection devices are essential for minimizing complications.
- Specific technical considerations are necessary to optimize outcomes in elderly patients undergoing CAS.
Purpose:
Elderly patients have a higher risk of complications in carotid endarterectomy. The aim of the study was to evaluate whether carotid artery stenting (CAS) performed in octogenarians also increases the procedure related risk.
Methods:
870 patients (male 626) mean age 70.9 +/- 9.3 years underwent 930 CAS for de novo lesions (n = 851) restenoses (n = 54) post radiation (n = 14) inflammatory arteritis (n = 9) post trauma aneurysms (n = 2). Indications for treatment: symptomatic carotid stenosis > or = 70% (n = 577) or asymptomatic stenosis > or = 80%. Patients were separated into two age groups: <80 years (749 patients, 806 CAS) and >80 years (121 patients, 124 CAS). 187 CAS performed without protection (N.P-) 6 patients >80 years, 743 with protection (NP+) (occlusion balloon: 334, filters: 404, reversal flow: 6) 118 patients >80 years. Data analysis included neurological complications, death and myocardial infarction (MI) rate at 30 days, anatomical particularities. Technical points will be described depending on the age of the patient.
Results:
Technical success 804/806 in patients <80 years, 123/124 in patients >80 years (NS). 30 days outcomes: in the patient group <80 years we observed 9 TIA (1.1%) 3 without NP (1.7%) 6 with NP (0.9%), 5 minor strokes (0.6%) 2 without NP (1.1%) 3 with NP (0.5%), 3 major strokes: 2 without NP (1.1%) 1 with NP (0.2%), 5 deaths (0.6%) 2 without NP (1.1%) 3 with NP (0.5%). Death/stroke/MI: 14 (1.8%) 6 without NP (3.3%), 8 with NP (1.3%). In the group >80 years, we observed 2 TIA (1.7%) 1 without NP 1 with NP (0.92%) 1 minor stroke without NP (17%) no major stroke, no death. Death/stroke/MI 1 without NP (17%).
Conclusion:
CAS can be performed in elderly patients without higher risk than in younger patients. But good indications, a meticulous technique, protection devices are mandatory and some technical points must be pointed out to avoid neurological complications and failures.
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