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Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Treatment Resistent Cancers02:56

Treatment Resistent Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

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Updated: Jul 2, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

COBALT-60 TELETHERAPY OF INTRA-ORAL CANCER.

W E Costolow, W R Wisdom

    California Medicine
    |April 1, 1956
    PubMed
    Summary
    This summary is machine-generated.

    Cobalt-60 teletherapy effectively reduced intra-oral cancer lesions in forty patients. This radiation therapy offers physical advantages, suggesting its use before considering surgery for oral cancers.

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    Area of Science:

    • Oncology
    • Radiation Oncology
    • Medical Physics

    Background:

    • Intra-oral cancer presents significant treatment challenges.
    • Conventional therapies may involve substantial side effects.
    • The need for precise radiation delivery in head and neck cancers is critical.

    Purpose of the Study:

    • To evaluate the efficacy of cobalt-60 teletherapy for intra-oral cancer.
    • To assess the physical advantages of cobalt-60 teletherapy in this context.
    • To determine the potential role of cobalt-60 teletherapy as a primary treatment modality.

    Main Methods:

    • Forty patients diagnosed with intra-oral cancer were treated.
    • Cobalt-60 teletherapy was administered directly to the primary tumor site.
    • Patients were observed to assess treatment response and side effects.

    Main Results:

    • The study observed a consistent and significant disappearance of the primary intra-oral lesions.
    • Cobalt-60 teletherapy demonstrated physical benefits including precise beam direction, reduced scatter, and minimized skin and bone effects.
    • While long-term cure rates were not yet established, the immediate lesion response was notable.

    Conclusions:

    • Cobalt-60 teletherapy shows promise as an effective treatment for intra-oral cancer.
    • The physical advantages of this modality make it a favorable option.
    • The authors recommend considering cobalt-60 teletherapy prior to radical surgical interventions for intra-oral malignancies.