Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Serum bile acids in normal pregnancy.

J Carter1

  • 1King George V Memorial Hospital, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

British Journal of Obstetrics and Gynaecology
|June 1, 1991
PubMed
Summary

Serum bile acid levels significantly increase during normal pregnancy. This longitudinal study tracked 56 women, observing rising postprandial bile acid concentrations from mid-pregnancy to term.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recent aqueous alteration associated to sedimentary volcanism on Mars.

Communications earth & environment·2025
Same author

Calibration of MAJIS (Moons and Jupiter Imaging Spectrometer). IV. Radiometric calibration (invited).

The Review of scientific instruments·2024
Same author

Calibration of MAJIS (Moons and Jupiter Imaging Spectrometer): V. Validation with mineral samples and reference materials.

The Review of scientific instruments·2024
Same author

Socioeconomic and ethnic disparities in preterm births in an English maternity setting: a population-based study of 1.3 million births.

BMC medicine·2024
Same author

Phase Ib dose-escalation trial of taselisib (GDC-0032) in combination with HER2-directed therapies in patients with advanced HER2+ breast cancer.

ESMO open·2024
Same author

Rare ^{40}K Decay with Implications for Fundamental Physics and Geochronology.

Physical review letters·2023

Area of Science:

  • Biochemistry
  • Obstetrics
  • Physiology

Background:

  • Bile acids are crucial for digestion and metabolism.
  • Pregnancy involves significant physiological changes that can affect metabolic processes.
  • Understanding metabolic shifts during pregnancy is vital for maternal and fetal health.

Purpose of the Study:

  • To investigate the longitudinal changes in serum bile acid levels during normal pregnancy.
  • To determine if postprandial serum bile acid concentrations change significantly as pregnancy progresses.

Main Methods:

  • A longitudinal study design was employed.
  • Serum bile acid levels were measured in 56 women throughout their pregnancy.
  • Postprandial serum bile acid concentrations were assessed at multiple visits.

Main Results:

  • Mean serum bile acid levels showed a significant increase from 16 weeks gestation to term.
  • Levels rose from 5.3 (2 SD 3.4) mumol/l at 16 weeks to 6.5 (2 SD 3.7) mumol/l at term.
  • The observed increase was statistically significant (P < 0.005).

Conclusions:

  • Serum bile acid levels progressively increase during normal pregnancy.
  • These findings highlight a normal physiological adaptation of bile acid metabolism in pregnancy.
  • Further research may explore the clinical implications of these changes.

Related Experiment Videos