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Simultaneous determination of sulphathiazole and sulphanilamide in pharmaceuticals by derivative spectrophotometry
J J Berzas Nevado1, F Salinas, I de Orbe Paya
1Departamento de Química Analítica, Facultad de Ciencias, Universidad de Extremadura, Badajoz, Spain.
Journal of Pharmaceutical and Biomedical Analysis
|January 1, 1991
Abstract:
Third-order and fourth-order derivative spectra have been used for determining sulphathiazole, sulphanilamide and their binary mixtures. The method is suitable for 1-22 micrograms ml-1 of sulphathiazole and for 0.5-14 micrograms ml-1 of sulphanilamide and can be applied for determining the sulphonamides in pharmaceuticals.