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Related Experiment Videos

[Oral and maxillofacial multiple primary cancers].

G C Lin1

  • 1School of Stomatology, Shanghai Second Medical University.

Zhonghua Kou Qiang Yi Xue Za Zhi = Zhonghua Kouqiang Yixue Zazhi = Chinese Journal of Stomatology
|March 1, 1991
PubMed
Summary
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This study found that 1.63% of patients with oral and maxillofacial cancers developed multiple primary lesions. Aggressive surgery is recommended for these complex cases to improve survival rates.

Area of Science:

  • Oncology
  • Oral and Maxillofacial Surgery

Context:

  • This retrospective study analyzed 2989 patients treated for oral and maxillofacial cancers between 1953 and 1985.
  • Identified 49 cases (1.63%) with multiple primary lesions.

Purpose:

  • To investigate the incidence, patterns, and survival rates of multiple primary oral and maxillofacial cancers.
  • To evaluate the effectiveness of surgical intervention for these cases.

Summary:

  • 49 patients (1.63%) presented with multiple primary oral and maxillofacial cancers.
  • The majority (89.8%) had double primary cancers, with foci occurring within a single organ, different organ systems, or across two systems.
  • Follow-up data over 3-27 years showed 3-year survival at 76%, 5-year at 69%, 10-year at 42%, and 15-year at 33%.

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Impact:

  • Highlights the occurrence and prognostic factors of multiple primary oral and maxillofacial cancers.
  • Emphasizes the necessity of aggressive surgical intervention for improved therapeutic outcomes in managing these complex oncological conditions.