[Clinical study on changes in insulin, C-peptide and glucagon during cardiopulmonary bypass]

Insulin, C-peptide and glucagon levels in plasma from 13 patients during cardiopulmonary bypass (CPB) were measured. Insulin level was higher during and after CPB than the level before operation (P less than 0.01 or 0.01 less than P less than 0.05). C-peptide level during and after CPB was much higher than the level before operation (P less than 0.01). There were no changes in glucagon level in CPB patients. The mechanism of these changes and clinical significances were discussed.