The otolaryngic manifestations of multiple sclerosis

Multiple sclerosis is a disease characterized pathologically by the disseminated demyelination of central nervous system white matter and clinically by episodes of focal neurologic deficit that occur in a relapsing and remitting course usually over many years. In most cases progressively fixed deficits occur with resultant moderate to severe disability. Symptoms and signs of multiple sclerosis are reviewed, with emphasis placed on the protean manifestations and natural history of the disease.