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Other Disorders of Digestive System

Other Disorders of Digestive System

The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...

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Chronic Bowel Disorders: Introduction

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Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...

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Related Experiment Video

Updated: Jul 2, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Published on: May 10, 2024

[Diffuse abdominal pain and eosinophilia].

W Hochholzer¹, S R Vavricka, G Stussi

¹Medizinische Poliklinik, Universitätsspital Basel, Basel.

|August 30, 2008

Summary

This summary is machine-generated.

Eosinophilic gastroenteritis is a rare gastrointestinal disorder. Diagnosis involves patient history, lab tests, and biopsies, with treatments ranging from antidiarrheals to corticosteroids.

Related Experiment Videos

Last Updated: Jul 2, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

Published on: May 10, 2024

Area of Science:

Gastroenterology
Immunology

Background:

Eosinophilic gastroenteritis (EG) is a rare condition with unknown causes and varied pathology.
Differential diagnoses include parasitic infections, hypereosinophilic syndrome, lymphoma, and allergies.

Observation:

Diagnosis is typically achieved through patient history, routine laboratory tests, and endoscopic biopsies or paracentesis.
Mild cases with diarrhea may respond to antidiarrheal medications.

Findings:

Corticosteroids are the standard treatment for more symptomatic patients with eosinophilic gastroenteritis.
The condition's heterogeneity requires careful diagnostic evaluation.

Implications:

Accurate diagnosis is crucial for effective management of eosinophilic gastroenteritis.
Further research into the etiology and targeted therapies for EG is warranted.