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Coryneform bacteria are gram-positive, aerobic, nonmotile rods that exhibit irregular, club-shaped, or V-shaped arrangements. Their V-shape results from snapping division, where the inner cell wall layer forms the cross-wall, while the outer layer remains intact until it ruptures on one side, causing the daughter cells to bend away.The primary genera are Corynebacterium and Arthrobacter. Corynebacterium includes diverse species, ranging from saprophytes to pathogens like Corynebacterium...
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Mechanisms of resistance to daptomycin in Staphylococcus aureus.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2017
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Enterococcus faecium small colony variant endocarditis in an immunocompetent patient.

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Comparative in vitro activity of tigecycline against enterobacteria producing two or more extended-spectrum beta-lactamases.

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Time-Lapse Epifluorescence Microscopy Imaging of Pseudomonas aeruginosa and Staphylococcus aureus Heterogeneous Phenotypes
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[Problematic bacteria].

J L Muñoz Bellido1

  • 1Departamento de Microbiologia, Hospital Universitario de Salamanca, Salamanca, Spain. jlmubel@usal.es

Revista Espanola De Quimioterapia : Publicacion Oficial De La Sociedad Espanola De Quimioterapia
|November 26, 2008
PubMed
Summary
This summary is machine-generated.

Multiresistant microorganism infections pose a significant threat to critical patients. Combating these infections and developing new antimicrobials are key challenges in intensive care units (ICUs).

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Area of Science:

  • Infectious diseases
  • Microbiology
  • Critical care medicine

Context:

  • Critical patients are highly susceptible to infections.
  • Multiresistant microorganisms (MDROs) are a growing concern in intensive care units (ICUs).
  • Specific MDROs like MRSA, BLEE, carbapenem-resistant A. baumannii, and P. aeruginosa present significant challenges.

Purpose:

  • To review the prevalence and characteristics of multidrug-resistant infections in critical patients.
  • To highlight the increasing resistance patterns of common pathogens in ICUs.
  • To underscore the challenges in managing and treating these infections.

Summary:

  • The prevalence of Methicillin-resistant Staphylococcus aureus (MRSA) is high in ICUs, with significant co-resistance to fluoroquinolones and macrolides.
  • Extended-spectrum beta-lactamase (BLEE) producing enterobacteria and carbapenem-resistant Acinetobacter baumannii are increasing, often exhibiting co-resistance to fluoroquinolones.
  • Pseudomonas aeruginosa shows stable but high resistance rates to common antibiotics, with a notable increase in multidrug resistance.

Impact:

  • Multiresistant bacteria infections are a major problem in critical care settings.
  • Effective control of MDRO spread and development of novel antimicrobials are crucial challenges.
  • Understanding resistance trends is vital for guiding treatment strategies and infection control measures.