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Updated: Jul 2, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Fatal very late stent thrombosis in a young diabetic patient with severely diffuse coronary atherosclerosis
Tadayuki Kadohira1, Yoshio Kobayashi, Tatsuhiko Asano
1Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.
Insights
Fatal stent thrombosis occurred in a young diabetic patient due to poor adherence to treatment. This highlights the risks of drug-eluting stents (DES) and the critical need for patient education on dual antiplatelet therapy.
Area of Science:
- Cardiology
- Endocrinology
- Medical Case Reports
Background:
- Stent thrombosis is a rare but serious complication of coronary stenting.
- Long-term antiplatelet therapy is crucial for preventing late stent thrombosis after drug-eluting stent (DES) implantation.
- Diabetic patients with poor glycemic control often exhibit diffuse coronary atherosclerosis and microvascular complications.
Observation:
- This case report details a fatal instance of very late stent thrombosis in a young patient with diabetes.
- The patient demonstrated nonadherence to prescribed diabetic treatments.
- The patient had severely diffuse coronary atherosclerosis.
Findings:
- Nonadherence to diabetic treatment contributed to advanced atherosclerosis.
- Drug-eluting stents (DES) may pose risks in diabetic patients with acute myocardial infarction.
- Very late stent thrombosis can be fatal, even in young patients.
Implications:
- Emphasizes the critical importance of patient education regarding long-term dual antiplatelet therapy adherence after DES implantation.
- Highlights the increased risk of cardiovascular complications in diabetic patients with poor glycemic control.
- Underscores the need for vigilant monitoring and management of diabetes in patients undergoing coronary stenting.
Abstract:
Stent thrombosis is an infrequent event but a potentially fatal complication of coronary stenting. Adherence to long-term antiplatelet therapy plays an important role in the prevention of late stent thrombosis after drug-eluting stent (DES) implantation. Poor glycemic control due to nonadherence to diabetic treatments is likely to result in severely diffuse coronary atherosclerosis and diabetic microvascular complications. This case report describes fatal very late stent thrombosis in a young diabetic patient, which teaches us about the potential risk of DES in patients with acute myocardial infarction and the importance of patient education about long-term dual antiplatelet therapy after DES implantation. Furthermore, it demonstrates severely diffuse atherosclerosis in a young diabetic patient with nonadherence to diabetic treatments.
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