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Published on: April 19, 2013

Associations between polymorphisms in the mitochondrial uncoupling proteins (UCPs) with T2DM.

Hye-Ja Lee1, Ha-Jung Ryu, Hyoung-Doo Shin

  • 1Division of Metabolic Disease, Center for Biomedical Sciences, National Institute of Health, 5 Nokbun-dong, Eunpyung-gu, Seoul, 122-701, Republic of Korea.

Clinica Chimica Acta; International Journal of Clinical Chemistry
|August 30, 2008
PubMed
Summary

Genetic variations in UCP2 and UCP3 genes are linked to type 2 diabetes mellitus (T2DM) susceptibility in Koreans. Specifically, UCP2 -5331G>A and UCP3 -2078C>T polymorphisms may indicate increased T2DM risk, particularly in women.

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