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Related Experiment Video

Updated: Jul 2, 2026

Calibration-free In Vitro Quantification of Protein Homo-oligomerization Using Commercial Instrumentation and Free, Open Source Brightness Analysis Software

Calibration-free In Vitro Quantification of Protein Homo-oligomerization Using Commercial Instrumentation and Free, Open Source Brightness Analysis Software

Published on: July 17, 2018

The BRIGHT tool.

Ngaire Kerse¹, Michal Boyd, Chris McLean

¹Department of General Practice and Primary Health Care, School of Population Health, University of Auckland, Private Bag 92019, New Zealand. n.kerse@auckland.ac.nz

|August 30, 2008

Summary

The Brief Risk Identification of Geriatric Health Tool (BRIGHT) questionnaire effectively identifies older adults with disabilities in the community. It is useful for detecting unmet needs and improving primary care surveillance.

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Calibration-free In Vitro Quantification of Protein Homo-oligomerization Using Commercial Instrumentation and Free, Open Source Brightness Analysis Software

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Area of Science:

Geriatric Health
Public Health Surveillance
Primary Care Medicine

Background:

The extent of unmet needs among community-dwelling older adults is largely unknown.
Accurate case-finding tools are essential for identifying individuals requiring support and intervention.

Purpose of the Study:

To validate the Brief Risk Identification of Geriatric Health Tool (BRIGHT) questionnaire for case-finding of disabilities in older adults living in the community.
To assess the BRIGHT questionnaire's utility in identifying unmet needs.

Main Methods:

101 community-dwelling participants aged 75+ completed the BRIGHT questionnaire twice.
Participants underwent a comprehensive geriatric assessment using the Minimum Dataset for Home Care (MDS-HC).
BRIGHT questionnaire reliability and validity were assessed against MDS-HC outputs (IADL CAP and MAPLe score).

Main Results:

The BRIGHT questionnaire demonstrated modest test-retest reliability (correlation of 0.77).
It showed a sensitivity of 0.86 and specificity of 0.86 for identifying disability when compared to the IADL CAP.
A sensitivity of 0.65 and specificity of 0.84 were observed against the MAPLe score.

Conclusions:

The BRIGHT questionnaire is a valuable tool for identifying community-dwelling older adults with disabilities.
It possesses excellent utility in ruling out individuals who do not require further assessment.
This tool can aid in detecting unmet needs and enhancing primary care surveillance.