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Maculopapular eruption secondary to itraconazole.
Tanja Batinac1, Gordana Zamolo, Biserka Troselj-Vukić
1Department of Dermatovenerology, University Hospital Center Rijeka, Rijeka, Croatia. tanjabatinac@net.hr
Collegium Antropologicum
|September 2, 2008
Summary
Adverse cutaneous reactions to itraconazole are rare but can occur. This case highlights a maculopapular eruption as a potential side effect during antifungal therapy.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Italconazole is a widely used antifungal medication.
- Adverse cutaneous reactions to itraconazole are documented as rare.
Observation:
- A 39-year-old woman developed pruritus on the 7th day of itraconazole therapy for hand onychomycosis.
- A symmetric, maculopapular eruption appeared on her upper torso, neck, trunk, and pressure-bearing areas, progressing to extremities.
Findings:
- The patient experienced a significant maculopapular reaction attributed to itraconazole.
- The eruption was morbiliform, confluent, and spread systemically.
Implications:
- Increased itraconazole usage necessitates awareness of potential rare allergic reactions.
- Clinicians should consider itraconazole-induced cutaneous reactions in patients presenting with similar dermatological symptoms.
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