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Total knee arthroplasty in osteogenesis imperfecta: case report
Akinobu Nishimura1, Masahiro Hasegawa, Ko Kato
1Department of Orthopaedic Surgery, Graduate School of Medicine, Mie University, Tsu City, Mie, Japan. meiten@clin.medic.mie-u.ac.jp
The Knee
|September 2, 2008
Summary
Osteogenesis imperfecta (OI) patients may benefit from knee replacement surgery for severe osteoarthritis. This rare case highlights a successful total knee arthroplasty in an adult OI patient, improving mobility and pain.
Area of Science:
- Orthopedics
- Genetics
- Rheumatology
Background:
- Osteogenesis imperfecta (OI) is a rare genetic collagen disorder causing brittle bones.
- Increased lifespan in OI patients reveals a high incidence of knee osteoarthritis.
- OI affects collagen-rich tissues, leading to diverse systemic complications.
Observation:
- A 53-year-old man with OI presented with severe bilateral knee pain and proximal femur deformities.
- The patient experienced post-traumatic osteoarthritis despite a 17-year fracture-free period.
- Bone mineral density was significantly low for his age.
Findings:
- The patient underwent cemented total knee arthroplasty (TKA) on the left knee.
- One year post-surgery, the patient reported pain relief and improved ambulation without assistance.
- This represents one of the few reported cases of knee replacement in OI patients.
Implications:
- Total knee arthroplasty can be a viable treatment option for osteoarthritis in select OI patients.
- Successful TKA in OI may improve quality of life and functional independence.
- Further research is needed to establish TKA protocols for OI patients with knee osteoarthritis.
