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Updated: Aug 15, 2026

Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis
Published on: May 12, 2019
[Recurrent adenocarcinoma of the uterus]
E Tuskan1, B Lovrić, I Navratil
1Ginekolosko-porodajni odjel Medicinskog centra Karlovac.
Abstract:
In a 60-year-old woman because of postmenopausal haemorrhage diagnostic curettage was performed. The histopathologic finding was the adenocarcinoma of the endometrium. The clinical stage was Ib, grade 2 or respectively presumptive stage IV with regard to ultrasound and radiographic findings. After radical hysterectomy and the resection of the sigmoid colon, chemotherapy with cytostatics was applied for 6 months. Three months after chemotherapy the recurrence of the tumour in the vaginal formix and superficial inguinal lymph nodes metastases appeared. Colpectomy with the extirpation of vaginal carcinoma and inguinal lymphadenectomy were performed, followed by irradiation. The course of the disease has shown that when the cancer is located near the point of entry of the uterine tube, the diagnosis and, if needed, therapy should be extended to inguinal regions too.
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