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Updated: Jul 2, 2026

Standards for Quantitative Metalloproteomic Analysis Using Size Exclusion ICP-MS
Published on: April 13, 2016
Thematic series: metals in biology
1Department of Biochemistry and the Center in Molecular Toxicology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146, USA. f.guengerich@vanderbilt.edu
Abstract:
Metals are important in biochemistry, and the concentrations of many are highly regulated. This prologue introduces the thematic series "Metals in Biology," which includes minireviews on three metals: iron, copper, and selenium. Deficiencies and excesses of all three of these metals cause problems in human health. The three minireviews deal with regulation of iron homeostasis, the roles of copper metabolism in cell regulation and disease, and the functions of selenoproteins.
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