Endolumenal fundoplication with EsophyX: the initial North American experience
Related Experiment Video
Updated: Jul 2, 2026

Robotic Myotomy and Partial Fundoplication for Achalasia
Published on: August 11, 2023
Simon Bergman1, Dean J Mikami, Jeffrey W Hazey
1Department of Surgery, Center for Minimally Invasive Surgery, The Ohio State University, Columbus, Ohio 43210, USA.
Abstract:
EsophyX is a novel endolumenal therapeutic option for the treatment of gastroesophageal reflux disease (GERD). The device is passed into the stomach, where it deploys a series of full-thickness fasteners to create a neogastroesophageal valve. The objective of this study was to demonstrate the safety and characterize the effectiveness of this approach in the initial North American experience. This is a retrospective study of consecutive patients with GERD who had undergone endolumenal fundoplication with the EsophyX device. At follow-up, proton pump inhibitor usage was elicited and 2 validated questionnaires were administered measuring GERD health-related quality of life (range 0-50) and symptom severity (range 0-72). In limited preliminary evaluation, the initial North American experience with endolumenal fundoplication using the EsophyX device is that it appears to be safe and provides moderate effectiveness in treating the symptoms of GERD. Further studies comparing this technique with conventional medical and surgical therapies are necessary.
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