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Published on: February 9, 2019
ShmR is essential for utilization of heme as a nutritional iron source in Sinorhizobium meliloti
Vanesa Amarelle1, Mark R O'Brian, Elena Fabiano
1Laboratorio de Ecología Microbiana, Instituto de Investigaciones Biológicas Clemente Estable, MEC, Unidad Asociada a la Facultad de Ciencias, Montevideo 11600, Uruguay.
Abstract:
The bacterium Sinorhizobium meliloti is able to use heme as a nutritional iron source. Here, we show that the iron-regulated shmR gene encodes an outer membrane protein required for growth on heme. Furthermore, an shmR mutant is resistant to the toxic heme analog gallium protoporphyrin. Thus, the receptor protein of the heme transport system has been identified in S. meliloti.
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