Related Experiment Video
Updated: Jul 2, 2026

Identifying Amino Acid Overproducers Using Rare-Codon-Rich Markers
Published on: June 24, 2019
An analysis of initiation codon utilization in the Domain Bacteria - concerns about the quality of bacterial genome
Andre Villegas1, Andrew M Kropinski2,1
1Public Health Agency of Canada, Laboratory for Foodborne Zoonoses, Guelph, ON N1G 3W4, Canada.
Abstract:
Using custom software (Inidon) we have examined the initiation codon utilization in 620 complete bacterial genomes downloaded from the National Center for Biotechnology Information (NCBI). The mean utilization of ATG, GTG and TTG codons is 80.1, 11.6 and 7.8 %, respectively. In most cases in which similar species or strains have been analysed the utilization percentages of the three initiation codons are remarkably similar, but in certain cases the results exhibit significant differences.
Related Concept Videos
Initiation of Translation
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
Genomic DNA in Prokaryotes
Genomic Diversity in Bacteria
Although bacterial genomes are much...
Genome Annotation and Assembly
Leaky Scanning
Modern Molecular Taxonomy
Prokaryotic Gene Structure and Organization

