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A Protocol for Analyzing Hepatitis C Virus Replication
Published on: June 26, 2014
Access to treatment of hepatitis C in prison inmates
Paul Strock1, Joël Mossong, Karine Hawotte
1Hepatogastroenterology, Service d'Hépato-Gastroentérologie, Centre Hospitalier de Luxembourg, Luxembourg-City, Luxembourg. strock.paul@chl.lu
Abstract:
We conducted a prospective study to investigate access to treatment in hepatitis C in 268 prisoners. Hepatitis C positivity had been known for 182 prisoners previously and 19 reported previous attempts to treat (10%). In comparison, during our study, 86/268 prisoners (32%) started therapy (P < 0.0001). They represented 41% of 211 prisoners with a positive viral load. In the genotype 2 or 3 group, 46 prisoners (50%) started therapy versus 40 prisoners (33%) with other genotypes (P = 0.01). This difference was due to prisoners waiting for liver biopsy. On an intention to treat basis, 45 prisoners (52%) achieved sustained virological response 6 months after the end of therapy. We conclude that a stay in prison is an effective opportunity to treat a group of hepatitis C patients which otherwise have very limited access to therapy.
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