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Updated: Jul 2, 2026

Native Cell Membrane Nanoparticles System for Membrane Protein-Protein Interaction Analysis
Published on: July 16, 2020
Investigation of cation-pi interactions in biological systems
1Department of Chemistry, University of Waterloo, Waterloo, Ontario, Canada N2L 3G1.
Abstract:
Noncovalent interactions, such as van der Waals interactions, hydrogen bonds, salt bridge and cation-Pi interactions play extremely important roles in biological systems and, in contrast to covalent bonds, many such noncovalent interactions are not well understood. In the present work a new protocol has been developed to measure the enhancement of binding energies due to cation-Pi interactions between aromatic amino acids and organic or metal ions. Investigation of the cation-Pi interactions will provide further insight into the structure and function of biological molecules.
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