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Choroidal metastasis from renal cell carcinoma presenting with cataract
Khawaja Khalid Shoaib1, Inam Ul Haq, Kashif Ali
1Department of Eye, Combined Military Hospital, Kharian. kkshoaib@hotmail.com
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|September 2, 2008
Summary
This case study details rare eye metastasis from renal cell carcinoma (RCC) presenting 8 years post-surgery. The tumor caused a cataract, vitreous involvement, and retinal detachment, confirmed by histopathology.
Area of Science:
- Ophthalmology
- Oncology
- Pathology
Background:
- Renal cell carcinoma (RCC) is a kidney cancer with potential for distant metastasis.
- Ocular metastasis from RCC is uncommon, presenting diagnostic and therapeutic challenges.
- Late recurrence of RCC metastasis, even years after primary tumor removal, requires vigilance.
Observation:
- A patient presented with a cataract, suspected to be induced by an underlying tumor.
- Following cataract extraction, further ocular complications including vitreous involvement and retinal detachment were observed.
- An extraocular mass was also detected and subsequently excised.
Findings:
- Histopathology confirmed choroidal metastasis from renal cell carcinoma (RCC) in the ocular tumor.
- Metastatic RCC was also identified in the excised extraocular mass and vitreous samples.
- This represents a rare instance of ocular involvement by RCC 8 years after nephrectomy.
Implications:
- Highlights the importance of considering metastatic disease in unexplained ocular findings, even years after cancer treatment.
- Emphasizes the need for thorough diagnostic workup in cases of suspected ocular tumors, including metastatic evaluation.
- Suggests that long-term surveillance for metastatic RCC may be warranted in certain patient populations.
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