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[Brain microbleeds]

C Cordonnier1

  • 1Service de neurologie et pathologie neurovasculaire, clinique neurologique, hôpital Roger-Salengro, CHRU de Lille, 59037 Lille cedex, France. c-cordonnier@chru-lille.fr

Revue Neurologique
|September 2, 2008
PubMed

Insights

Brain microbleeds (MB), small brain lesions, are common in stroke patients and linked to hypertension. Their role in predicting future strokes requires further investigation.

Area of Science:

  • Neurology
  • Neuroradiology
  • Vascular Neurology

Context:

  • Brain microbleeds (MB) are focal lesions identified on T2* gradient echo MRI.
  • Prevalence varies: 5% in healthy individuals, 34% in ischemic stroke, and 60% in hemorrhagic stroke patients.
  • MB are distributed throughout the brain parenchyma.

Purpose:

  • To describe the characteristics, prevalence, and associations of brain microbleeds.
  • To explore the potential link between MB and cerebrovascular diseases like hypertension, lacunae, and leukoaraiosis.
  • To discuss the controversial diagnostic and prognostic value of MB in stroke risk.

Summary:

  • Brain microbleeds (MB) are small, focal lesions appearing as hyposignal on T2* MRI.
  • They are frequently observed in patients with stroke and hypertension, and associated with other small vessel disease markers.
  • While potentially indicating increased future stroke risk, their clinical utility is debated.

Impact:

  • Highlights MB as potential biomarkers for microangiopathy severity.
  • Underscores the association of MB with hypertension and other neuroimaging findings.
  • Emphasizes the need for further research to clarify the diagnostic and prognostic significance of MB.

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