Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
The Blood-brain Barrier00:49

The Blood-brain Barrier

Overview

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transient ischemic attack care pathways in stroke units: Findings from a French nationwide survey.

Revue neurologique·2025
Same author

Tenecteplase in acute ischemic stroke: Review of the literature and expert consensus from the French Neurovascular Society.

Revue neurologique·2022
Same author

Safety and outcome of mechanical thrombectomy in ischaemic stroke related to carotid artery dissection.

Journal of neurology·2021
Same author

Impact of recanalisation by mechanical thrombectomy in mild acute ischemic stroke with large anterior vessel occlusion.

Revue neurologique·2021
Same author

Career aspirations among specialty residents in France: a cross-sectional gender-based comparison.

BMC medical education·2021
Same author

The impact of anti-mould prophylaxis on Aspergillus PCR blood testing for the diagnosis of invasive aspergillosis.

The Journal of antimicrobial chemotherapy·2020
Same journal

Geographic disparities in MRI features of ischemic stroke and small vessel disease: A comparative study between French Guiana and mainland France. Findings from the BECATOUR multicenter registry.

Revue neurologique·2026
Same journal

Continuous subcutaneous perfusion of apomorphine in Parkinson's disease: Towards monotherapy?

Revue neurologique·2026
Same journal

Neuro-Whipple presenting as autoimmune encephalitis.

Revue neurologique·2026
Same journal

Multimodal assessment of minimally conscious state and cognitive motor dissociation in neurocritical care: A critical review.

Revue neurologique·2026
Same journal

Development of a new episodic memory assessment tool (NEM): Preliminary data and clinical perspectives.

Revue neurologique·2026
Same journal

Novel variants and rare clinical presentations in MFN2-related Charcot-Marie-Tooth disease: Insights from 10 families.

Revue neurologique·2026
See all related articles

Related Experiment Video

Updated: Jul 2, 2026

Sub-acute Cerebral Microhemorrhages Induced by Lipopolysaccharide Injection in Rats
06:39

Sub-acute Cerebral Microhemorrhages Induced by Lipopolysaccharide Injection in Rats

Published on: October 17, 2018

[Brain microbleeds].

C Cordonnier1

  • 1Service de neurologie et pathologie neurovasculaire, clinique neurologique, hôpital Roger-Salengro, CHRU de Lille, 59037 Lille cedex, France. c-cordonnier@chru-lille.fr

Revue Neurologique
|September 2, 2008
PubMed
Summary
This summary is machine-generated.

Brain microbleeds (MB), small brain lesions, are common in stroke patients and linked to hypertension. Their role in predicting future strokes requires further investigation.

More Related Videos

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
07:30

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Imaging Vital and Non-vital Brain Pericytes in Brain Slices following Subarachnoid Hemorrhage
05:11

Imaging Vital and Non-vital Brain Pericytes in Brain Slices following Subarachnoid Hemorrhage

Published on: August 18, 2023

Related Experiment Videos

Last Updated: Jul 2, 2026

Sub-acute Cerebral Microhemorrhages Induced by Lipopolysaccharide Injection in Rats
06:39

Sub-acute Cerebral Microhemorrhages Induced by Lipopolysaccharide Injection in Rats

Published on: October 17, 2018

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
07:30

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Imaging Vital and Non-vital Brain Pericytes in Brain Slices following Subarachnoid Hemorrhage
05:11

Imaging Vital and Non-vital Brain Pericytes in Brain Slices following Subarachnoid Hemorrhage

Published on: August 18, 2023

Area of Science:

  • Neurology
  • Neuroradiology
  • Vascular Neurology

Context:

  • Brain microbleeds (MB) are focal lesions identified on T2* gradient echo MRI.
  • Prevalence varies: 5% in healthy individuals, 34% in ischemic stroke, and 60% in hemorrhagic stroke patients.
  • MB are distributed throughout the brain parenchyma.

Purpose:

  • To describe the characteristics, prevalence, and associations of brain microbleeds.
  • To explore the potential link between MB and cerebrovascular diseases like hypertension, lacunae, and leukoaraiosis.
  • To discuss the controversial diagnostic and prognostic value of MB in stroke risk.

Summary:

  • Brain microbleeds (MB) are small, focal lesions appearing as hyposignal on T2* MRI.
  • They are frequently observed in patients with stroke and hypertension, and associated with other small vessel disease markers.
  • While potentially indicating increased future stroke risk, their clinical utility is debated.

Impact:

  • Highlights MB as potential biomarkers for microangiopathy severity.
  • Underscores the association of MB with hypertension and other neuroimaging findings.
  • Emphasizes the need for further research to clarify the diagnostic and prognostic significance of MB.