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Related Experiment Video

Updated: Jul 2, 2026

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid
03:47

Enhancement of Facial Rejuvenation Through a Combination of 1565 nm Non-Ablative Fractional Laser with 30% Supramolecular Salicylic Acid

Published on: September 27, 2024

Fractional laser skin therapy.

Marc Oliver Bodendorf1, Sonja Grunewald, Tino Wetzig

  • 1Department of Dermatology,Venerology and Allergology, University Hospital of Leipzig and University of Leipzig Medical School, Germany.

Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
|September 3, 2008
PubMed
Summary

Fractional laser treatments offer minimally invasive options for skin rejuvenation. New ablative systems using CO2 and Er:YAG lasers show promising results comparable to existing fractional ablative methods.

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Area of Science:

  • Dermatology
  • Aesthetic Medicine
  • Laser Technology

Background:

  • Chronically photodamaged skin necessitates advanced treatment options.
  • Minimally invasive fractional laser therapies promote dermal remodeling.
  • Fractional non-ablative thermal energy is a key mechanism.

Purpose of the Study:

  • To review current fractional laser interventions for photodamaged skin.
  • To evaluate newly introduced fractional ablative laser systems (CO2 and heated Er:YAG).
  • To incorporate personal experience and assess clinical efficacy.

Main Methods:

  • Review of existing literature and personal clinical experience.
  • Microscopic verification of treatment effects.
  • Testing of prototype fractional ablative laser systems.

Main Results:

  • Fractional ablative laser systems (CO2, heated Er:YAG) demonstrate clinical efficacy.
  • Microscopic analysis confirms dermal remodeling effects.
  • Initial results appear comparable to existing fractional ablative systems.

Conclusions:

  • Fractional ablative lasers offer effective, minimally invasive treatment for photodamaged skin.
  • Further systematic studies on clinical outcomes and system settings are required.
  • Combining ablative and non-ablative fractional technologies may enhance efficacy and safety.