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Updated: Jul 2, 2026

Retzius-Sparing Robot-Assisted Radical Prostatectomy
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Retzius-Sparing Robot-Assisted Radical Prostatectomy

Published on: May 19, 2022

[Nerve-sparing radical prostatectomy--effect and risks].

Michael Borre1

  • 1Arhus Universitetshospital, Skejby, Urinvejskirurgisk Afdeling K, Arhus N. borre@dadlnet.dk

Ugeskrift for Laeger
|September 3, 2008
PubMed
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Nerve-sparing radical prostatectomy (NSRP) preserves erectile function without compromising cancer control. Carefully selected patients benefit from this safe and effective technique, improving outcomes.

Area of Science:

  • Urology
  • Oncology
  • Surgical Technique

Context:

  • Radical prostatectomy (RP) is a primary treatment for prostate cancer.
  • Preserving neurovascular bundles during RP is crucial for maintaining erectile function.
  • Patient selection is key to successful nerve-sparing radical prostatectomy (NSRP).

Purpose:

  • To evaluate the efficacy of nerve-sparing radical prostatectomy (NSRP) in preserving postoperative erectile function.
  • To assess the oncological outcomes, specifically positive surgical margins and biochemical recurrence, following NSRP.
  • To compare functional and oncological results between NSRP and conventional RP.

Summary:

  • A study of 242 patients undergoing RP found that 84 were offered NSRP.
  • Postoperative erectile function was significantly better in the NSRP group compared to the non-NSRP group.

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  • NSRP did not increase the risk of positive surgical margins, with biochemical recurrence rates of 8%, 13%, and 20% for bilateral, unilateral, and non-NSRP, respectively.

    • Impact:

    • NSRP is a safe and effective procedure for carefully selected prostate cancer patients.
    • Preoperatively potent, low- to middle-risk patients (cT1-2a/b, Gleason score < 7, PSA < 10 ng/mL) are suitable candidates for NSRP.
    • This technique enhances quality of life by preserving erectile function post-prostatectomy.