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Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

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Updated: Jul 2, 2026

A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease
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[Inflammatory cloacogenic polyp].

Caroline Ewertsen1, Claus Bo Søndergaard Svendsen, Lars Bo Svendsen

  • 1Rigshospitalet, Radiologisk Klinik, Sektion for Ultralyd, Kirurgisk Gastroenterologisk Klinik, CTX, København Ø. caroline.ewertsen@dadlnet.dk

Ugeskrift for Laeger
|September 3, 2008
PubMed
Summary
This summary is machine-generated.

A case of inflammatory cloacogenic polyp (ICP) in a young adult highlights the importance of examining anal polyps. Histopathology confirmed ICP without dysplasia, though rare cases can show dysplasia.

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Published on: October 16, 2013

Area of Science:

  • Gastroenterology
  • Colorectal Surgery
  • Pathology

Background:

  • Inflammatory cloacogenic polyp (ICP) is a rare anal lesion.
  • Intermittent rectal bleeding can be a symptom of ICP.
  • Young adults may present with ICP without a prior medical or family history.

Observation:

  • A 28-year-old male presented with a four-year history of intermittent rectal bleeding.
  • Colonoscopy revealed anal polyps.
  • Histopathology confirmed inflammatory cloacogenic polyp without dysplasia.

Findings:

  • The case demonstrates a rare occurrence of inflammatory cloacogenic polyp in a young adult.
  • Histological examination confirmed the diagnosis, noting the rarity of dysplasia in ICP.
  • No dysplasia was identified in this particular case.

Implications:

  • Histological examination of perianal lesions is crucial, even in young patients.
  • Early diagnosis and histological assessment are important for managing ICP.
  • Understanding the spectrum of ICP, including rare dysplasia, is vital for patient care.