Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Frequency-dependent Selection01:21

Frequency-dependent Selection

When the fitness of a trait is influenced by how common it is (i.e., its frequency) relative to different traits within a population, this is referred to as frequency-dependent selection. Frequency-dependent selection may occur between species or within a single species. This type of selection can either be positive—with more common phenotypes having higher fitness—or negative, with rarer phenotypes conferring increased fitness.Positive Frequency-Dependent SelectionIn positive...
Types of Selection01:46

Types of Selection

Natural selection influences the frequencies of particular alleles and phenotypes within populations in several different ways. Primarily, natural selection can be directional, stabilizing, or disruptive. Directional selection favors one extreme trait and shifts the population towards that phenotype while selecting against individuals displaying alternate traits. Stabilizing selection favors an intermediate trait with a narrow range of variation. Deviation from the optimal phenotype towards an...
Understanding Species and Reproductive Barriers01:17

Understanding Species and Reproductive Barriers

A species is a group of organisms that interbreed and produce fertile offspring. Typically, individuals of the same species appear similar and share common characteristics due to their highly similar genomes. However, not all organisms that look alike are members of the same species. Various mechanisms keep most species discrete. While some mechanisms prevent reproductive behavior and fertilization (pre-zygotic isolation), others prevent the production of fertile offspring after mating has...
Mate Choice01:20

Mate Choice

Mate choice—the decision about whom to mate with—is a type of natural selection, since animals must reproduce to pass down their genes. Mate choice is also called intersexual selection because the behavior occurs between the sexes.
Spermatogenesis01:41

Spermatogenesis

Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male reproductive...
Genetic Variation01:25

Genetic Variation

Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
Genes exist in different versions called alleles, which...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Value of PGT-A when only one or two blastocysts are obtained: propensity-score matching and cost-effectiveness study.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2024
Same author

A novel machine-learning framework based on early embryo morphokinetics identifies a feature signature associated with blastocyst development.

Journal of ovarian research·2024
Same author

Role of thyroid stimulating hormone in the maintenance and functioning of the human corpus luteum.

Journal of endocrinological investigation·2024
Same author

No major differences in perinatal and maternal outcomes between uninterrupted embryo culture in time-lapse system and conventional embryo culture.

Human reproduction (Oxford, England)·2023
Same author

Improved clinical utility of preimplantation genetic testing through the integration of ploidy and common pathogenic microdeletions analyses.

Human reproduction (Oxford, England)·2023
Same author

The role of thyroid function in female and male infertility: a narrative review.

Journal of endocrinological investigation·2022

Related Experiment Video

Updated: Jul 2, 2026

Laser-assisted Microdissection (LAM) as a Tool for Transcriptional Profiling of Individual Cell Types
09:31

Laser-assisted Microdissection (LAM) as a Tool for Transcriptional Profiling of Individual Cell Types

Published on: May 10, 2016

Morphological selection of gametes.

F Ubaldi1, L Rienzi

  • 1G.EN.E.R.A. Centre for Reproductive Medicine, Valle Giulia Clinic, Via G. De Notaris 2, 00197 Rome, Italy. ubaldi.fm@tin.it

Placenta
|September 3, 2008
PubMed
Summary

Selecting gametes before intracytoplasmic sperm injection (ICSI) is crucial for avoiding excess embryos. Oocyte and sperm morphology offer potential indicators of embryo quality and fertilization success.

Area of Science:

  • Reproductive Medicine
  • Embryology
  • Gamete Biology

Background:

  • Selecting gametes before intracytoplasmic sperm injection (ICSI) is vital to prevent supernumerary embryo production for ethical, legal, or religious reasons.
  • Identifying early markers of embryo quality at the oocyte and sperm stage is essential for successful fertilization and development.

Purpose of the Study:

  • To investigate the predictive value of oocyte and sperm morphological abnormalities for fertilization and embryo development.
  • To evaluate the effectiveness of gamete selection methods prior to in vitro insemination.

Main Methods:

  • Oocyte competence assessed through morphological evaluation, including polar body appearance, perivitelline space, and cytoplasmic granularity.
  • Sperm morphology analyzed at high magnification (approx. 6300x) using advanced microscopy, focusing on nuclear abnormalities.

More Related Videos

Manipulation of Ploidy in Caenorhabditis elegans
07:54

Manipulation of Ploidy in Caenorhabditis elegans

Published on: March 15, 2018

Sperm Collection of Differential Quality Using Density Gradient Centrifugation
03:28

Sperm Collection of Differential Quality Using Density Gradient Centrifugation

Published on: November 29, 2018

Related Experiment Videos

Last Updated: Jul 2, 2026

Laser-assisted Microdissection (LAM) as a Tool for Transcriptional Profiling of Individual Cell Types
09:31

Laser-assisted Microdissection (LAM) as a Tool for Transcriptional Profiling of Individual Cell Types

Published on: May 10, 2016

Manipulation of Ploidy in Caenorhabditis elegans
07:54

Manipulation of Ploidy in Caenorhabditis elegans

Published on: March 15, 2018

Sperm Collection of Differential Quality Using Density Gradient Centrifugation
03:28

Sperm Collection of Differential Quality Using Density Gradient Centrifugation

Published on: November 29, 2018

  • Exploration of sperm selection based on hyaluronic acid binding as a potential biochemical marker.

    • Main Results:

    • Specific oocyte morphological abnormalities (e.g., abnormal polar body, large perivitelline space, cytoplasmic granularity) negatively impact fertilization and development.
    • Strict selection criteria for sperm morphology, particularly nuclear abnormalities, show a negative association with ICSI outcomes.
    • High-magnification real-time sperm observation may reveal relationships between defects and ICSI success.

    Conclusions:

    • Oocyte and sperm morphology can serve as indicators of gamete competence and potential for successful embryo development.
    • Further prospective randomized studies are necessary to validate the efficacy of proposed gamete selection criteria for in vitro insemination.