Amplatzer device closure of a tortuous Gerbode (left ventricle-to-right atrium) defect complicated by transient

Abraham Rothman1, Alvaro Galindo, Richard Channick

  • 1Department of Pediatrics, University of Nevada School of Medicine and Childrens Heart Center, Las Vegas, Nevada, USA. rothman@childrensheartcenter.com

Insights

Percutaneous closure of a Gerbode defect, a rare heart condition, successfully treated an elderly male with shortness of breath. The minimally invasive procedure improved his exercise tolerance and resolved the heart murmur.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Gerbode defect is a rare congenital or acquired intracardiac communication between the left ventricle and the right atrium.
  • Acquired Gerbode defects can occur secondary to endocarditis, trauma, or cardiac surgery, often presenting with symptoms of heart failure or pulmonary hypertension.

Observation:

  • An 86-year-old male with a history of mitral valve surgery presented with progressive dyspnea and a cardiac murmur.
  • Echocardiography identified a significant left ventricular-to-right atrial communication, consistent with a Gerbode defect.

Findings:

  • The Gerbode defect was successfully closed percutaneously using an Amplatzer Septal Occluder.
  • The patient experienced transient postoperative hemolysis and renal dysfunction, which resolved spontaneously.
  • One-year follow-up demonstrated no residual shunt on echocardiography and significant improvement in the patient's exercise tolerance.

Implications:

  • Percutaneous closure is a viable and effective alternative to surgical repair for Gerbode defects, particularly in elderly or high-risk patients.
  • Minimally invasive techniques can lead to improved patient outcomes and reduced recovery times.
  • This case highlights the importance of echocardiography in diagnosing complex intracardiac shunts and the efficacy of device closure for acquired Gerbode defects.