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Published on: December 23, 2022
Amplatzer device closure of a tortuous Gerbode (left ventricle-to-right atrium) defect complicated by transient
Abraham Rothman1, Alvaro Galindo, Richard Channick
1Department of Pediatrics, University of Nevada School of Medicine and Childrens Heart Center, Las Vegas, Nevada, USA. rothman@childrensheartcenter.com
Insights
Percutaneous closure of a Gerbode defect, a rare heart condition, successfully treated an elderly male with shortness of breath. The minimally invasive procedure improved his exercise tolerance and resolved the heart murmur.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Gerbode defect is a rare congenital or acquired intracardiac communication between the left ventricle and the right atrium.
- Acquired Gerbode defects can occur secondary to endocarditis, trauma, or cardiac surgery, often presenting with symptoms of heart failure or pulmonary hypertension.
Observation:
- An 86-year-old male with a history of mitral valve surgery presented with progressive dyspnea and a cardiac murmur.
- Echocardiography identified a significant left ventricular-to-right atrial communication, consistent with a Gerbode defect.
Findings:
- The Gerbode defect was successfully closed percutaneously using an Amplatzer Septal Occluder.
- The patient experienced transient postoperative hemolysis and renal dysfunction, which resolved spontaneously.
- One-year follow-up demonstrated no residual shunt on echocardiography and significant improvement in the patient's exercise tolerance.
Implications:
- Percutaneous closure is a viable and effective alternative to surgical repair for Gerbode defects, particularly in elderly or high-risk patients.
- Minimally invasive techniques can lead to improved patient outcomes and reduced recovery times.
- This case highlights the importance of echocardiography in diagnosing complex intracardiac shunts and the efficacy of device closure for acquired Gerbode defects.
Abstract:
An 86 year-old male presented with progressive shortness of breath and a murmur. Six years earlier, he had undergone mitral valve surgery. An echocardiogram revealed a significant left ventricular-to-right atrial connection (Gerbode defect). The defect was closed percutaneously using an Amplatzer Septal Occluder device. After the procedure, the patient developed transient hemolysis and renal dysfunction. A year later, there was no residual flow on echocardiography and the patient reported marked improvement in exercise tolerance.
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