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Related Experiment Video

Updated: Jul 2, 2026

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
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Contemporary inguinal lymph node dissection: minimizing complications.

Philippe E Spiess1, Mike S Hernandez, Curtis A Pettaway

  • 1H. Lee Moffitt Cancer Center & Research Institute, 12902 Magnolia Drive, Office # 4035C, Tampa, FL 33612-9415, USA. Philippe.spiess@moffitt.org

World Journal of Urology
|September 3, 2008
PubMed
Summary
This summary is machine-generated.

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Inguinal lymph node dissection for penile cancer traditionally had high morbidity, but recent modifications significantly reduce complications. Novel strategies have decreased surgical risks for staging and therapy.

Area of Science:

  • Urology
  • Surgical Oncology
  • Oncology

Background:

  • Penile cancer management often requires inguinal lymph node dissection (ILND).
  • ILND is associated with significant surgical morbidity, including skin necrosis, infection, and lymphedema.
  • Historically, complication rates for ILND range from 80-100%.

Purpose of the Study:

  • To review the morbidity associated with ILND in penile cancer patients.
  • To describe recent modifications aimed at reducing ILND complications.
  • To report contemporary complication rates and compare them with historical data.

Main Methods:

  • Literature review of studies on ILND complications for penile cancer using PubMed.
  • Analysis of contemporary patient data regarding morbidity from ILND.

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  • Comparison of current complication rates with previously reported series.

    • Main Results:

    • A literature review identified 27 relevant manuscripts over 25 years.
    • Recent technical modifications and management strategies have reduced ILND risks.
    • Contemporary complication rates for diagnostic ILND were 19% minor and 27% major; for therapeutic ILND, 29% minor and 24% major.
    • Dynamic sentinel lymph node biopsy showed a 7% complication rate in node-negative patients.

    Conclusions:

    • Novel management strategies and surgical modifications have decreased peri-operative morbidity.
    • These advancements improve the safety of inguinal staging and therapy for penile cancer.
    • Minimally invasive techniques like sentinel lymph node biopsy offer lower complication rates.