Related Experiment Video
Updated: Jul 2, 2026
09:10
Synthesis of Masarimycin, a Small Molecule Inhibitor of Gram-Positive Bacterial Growth
Published on: January 7, 2022
Total synthesis of salinosporamide A
Takeo Fukuda1, Kouhei Sugiyama, Shiho Arima
1School of Pharmacy, Kitasato University, Kitasato Institute for Life Sciences, Kitasato University, and The Kitasato Institute, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan.
Organic Letters
|September 4, 2008
Abstract:
The total synthesis of salinosporamide A has been achieved through enzymatic desymmetrization, diastereoselective aldol reaction, intramolecular aldol reaction, and intermolecular Reformatsky-type reaction followed by 1,4-reduction as key reactions.
