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Local toxicity with subcutaneous methadone. Experience of two centers
E Bruera1, R Fainsinger, M Moore
1Palliative Care Unit, Pharmacy Dept., Edmonton General Hospital, Edmonton, AlbertaCanada Palliative Care Service, National Cancer Institute, MilanItaly.
Pain
|May 1, 1991
Abstract:
We report on 8 patients treated with subcutaneous methadone for cancer-related pain at 2 institutions. The success of other subcutaneous agents for pain control has been well demonstrated. It was felt that methadone would be useful due to its low cost. Unfortunately, 7 of the 8 patients experienced adverse reactions at the subcutaneous sites requiring cessation of subcutaneous methadone.