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Two pregnancies in a Cushing's syndrome. Case report
L A Da Motta1, L D Motta, A M Barbosa
1Division of Endocrinology, University of Brasilia, Brazil.
Panminerva Medica
|January 1, 1991
Summary
Cushing's syndrome in pregnancy is rare but manageable. Early diagnosis and surgical treatment of adrenal adenoma during pregnancy can lead to successful outcomes for both mother and child.
Area of Science:
- Endocrinology
- Reproductive Medicine
- Surgical Oncology
Background:
- Cushing's syndrome, characterized by prolonged exposure to excess cortisol, poses significant risks during pregnancy.
- Pregnancy is infrequently reported in women with Cushing's syndrome due to potential fertility issues and complications.
- Adrenal adenomas are a common cause of Cushing's syndrome.
Purpose of the Study:
- To describe a case of successful pregnancy management in a patient with Cushing's syndrome.
- To highlight the importance of early diagnosis and surgical intervention for adrenal adenoma during pregnancy.
- To emphasize the positive maternal and fetal outcomes achievable with timely treatment.
Main Methods:
- Case report of a patient with Cushing's syndrome due to adrenal adenoma.
- Description of two pregnancies occurring during the course of the disease.
- Surgical resection of the adrenal adenoma during the second pregnancy.
Main Results:
- The patient experienced two pregnancies, with the first resulting in a premature birth (900g infant).
- Following surgical resection of the adrenal adenoma early in the second pregnancy, the patient delivered a full-term, healthy infant (4kg).
- Both children have demonstrated normal physical and neurological development post-delivery.
Conclusions:
- Early diagnosis of Cushing's syndrome in pregnant patients is crucial.
- Surgical treatment of adrenal adenoma during pregnancy is indicated to prevent maternal and fetal complications.
- Successful pregnancy outcomes are possible with prompt diagnosis and intervention for adrenal tumors causing Cushing's syndrome.