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Updated: Jul 2, 2026

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
Published on: April 27, 2014
Chronic pelvic pain syndrome and the overactive bladder: the inflammatory link
Rajiv Saini1, Ricardo R Gonzalez, Alexis E Te
1Department of Urology, Weill Cornell Medical College, 525 East 68th Street, New York, NY 10021, USA. ras2027@med.cornell.edu
Abstract:
Although the causes of chronic prostatitis/chronic pelvic pain syndrome, painful bladder syndrome/interstitial cystitis, and overactive bladder remain unclear, inflammation may explain some of the causative and propagating features. Cytokines may play a role by recruiting inflammatory cells and ultimately in inducing symptoms. This paper reviews the role of cytokines in the pathophysiology of chronic prostatitis/chronic pelvic pain syndrome, overactive bladder, and painful bladder syndrome/interstitial cystitis.
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