Metachromatic leukodystrophy: magnetic resonance imaging (diffusion weighted image--DWI)
Related Experiment Video
Updated: Jul 2, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
Published on: February 19, 2021
Zdenek Seidl1, Manuela Vaneckova, Tomas Vitak
1MRI Unit, Department of Radiology, 1st Medical Faculty, Charles University, Prague, Czech Republic. zseid@lf1.cuni.cz
Abstract:
Ten years old patient with juvenile form of metachromatic leukodystrophy (MDL) is presented. Apart from standard magnetic resonance (MR) protocol, the diffusion weighted sequence was performed and apparent diffusion coefficient (ADC) map was constructed. The cause of restricted diffusion is considered to be the deposits of metachromatic substance in the intercellular space, apparently similar reason for decrease of speed of diffusion in other storage diseases.
Related Concept Videos
Magnetic Resonance Imaging
Imaging Studies IV: Magnetic Resonance Imaging

