[Baseline predictors of outcome in stroke patients treated with intravenous thrombolysis--the Austrian stroke unit registry]
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Updated: Jul 2, 2026
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Raffi Topakian1, Hans-Peter Haring, Franz T Aichner
1Abteilung für Neurologie, Landesnervenklinik Wagner-Jauregg Linz, Linz, Austria. raffi.topakian@hotmail.com
Background:
Intravenous thrombolysis (IVT) for acute ischaemic stroke is safe and effective in routine clinical use. We aimed to identify baseline predictors of excellent outcome after 3 months, defined by a modified Rankin Scale score
Method:
We analysed data entered in the Austrian Stroke Unit Registry up to February 28th 2007.
Results:
Eight hundred and twelve patients received IVT after admission to a stroke unit within 3 hours of stroke onset. Of 386 patients with complete follow-up at 3 months, 201 (52.1%) had an excellent outcome. Multivariate regression analyses identified age (odds ratio (OR) 0.96; 95% confidence intervals (CI) 0.94-0.98; p<0.0005) and admission score on the National Institute of Health Stroke Scale (NIHSS; OR 0.87; 95% CI 0.84-0.91; p<0.0005) to be independent predictors of excellent outcome.
Conclusions:
Age and admission NIHSS score were found to powerfully predict outcome after IVT. However, results may be compromised by the loss to follow-up bias.
