Renal lesions in baby chicks due to sodium chloride poisoning

The pathogenesis is described of renal lesions which developed in 1-day-old chicks fed a ration containing 10% sodium chloride for 25 successive days. The gross lesions are described. Microscopically the kidneys showed that nephrosis and glomerular changes were very prominent. These included glomerular hypertrophy, formation of epithelial crescents, fibrous adhesions, lobularity, shrinkage and collapse of the glomerular tuft and thickening of the basement membrane of the capillary tuft. Segmental hyalinosis of the tuft was also sometimes observed.