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Updated: Jul 2, 2026

Assessment of Audio-Tactile Sensory Substitution Training in Participants with Profound Deafness Using the Event-Related Potential Technique
Published on: September 7, 2022
Word deafness as a cortical auditory processing deficit: a case report with MEG
Silke Jörgens1, Katja Biermann-Ruben, Martin W Kurz
1Department of Neurology, University Hospital, Düsseldorf, Germany. joergesi@uni-duesseldorf.de
Abstract:
Pure word deafness is a rare disorder dramatically impairing comprehension of spoken language, while auditory functions remain relatively intact. We present a 71-year-old woman with a slowly progressive disturbance of speech perception due to pure word deafness. MRI revealed degeneration of the temporal lobes. A magnetoencephalographic investigation using alternating single tone stimulation showed that N100 was followed by a second transient response and was abnormally prolonged up to 600-700 ms. We conclude that auditory processing is disturbed at long latency ranges following the N100, which may result in the clinical presentation of pure word deafness.
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